KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
8.79
Human Site:
Y214
Identified Species:
13.81
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
Y214
T
E
D
S
I
R
D
Y
E
D
G
M
E
V
D
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
G204
S
S
Q
Y
N
M
A
G
V
R
T
E
D
S
I
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
E185
R
D
Y
E
D
G
M
E
V
D
T
T
P
T
V
Dog
Lupus familis
XP_535567
226
24585
E208
R
D
Y
E
D
G
M
E
V
D
T
T
P
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
Y213
T
E
D
S
V
R
N
Y
E
D
G
M
E
V
E
Rat
Rattus norvegicus
Q04753
236
26074
Y213
T
E
D
S
V
R
T
Y
E
D
G
M
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
F224
T
D
D
S
S
R
D
F
E
G
A
R
F
R
F
Chicken
Gallus gallus
XP_423253
238
26615
F215
T
E
D
S
I
R
E
F
E
D
G
M
E
V
D
Frog
Xenopus laevis
P54106
241
26428
P218
T
E
G
P
A
L
E
P
E
D
G
M
D
V
E
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
F227
T
E
E
P
D
A
Q
F
E
D
G
M
E
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
G197
A
L
T
L
G
R
N
G
V
Q
N
L
S
L
D
Honey Bee
Apis mellifera
XP_624081
207
23224
A189
T
N
H
N
G
T
E
A
D
D
A
M
D
I
E
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
I187
G
L
A
N
M
Q
R
I
F
G
R
G
D
Q
H
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
N147
L
I
V
A
D
G
G
N
G
D
A
M
D
T
G
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
H213
L
E
L
Q
I
N
D
H
R
F
E
D
A
E
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
0
6.6
6.6
N.A.
80
80
N.A.
40
86.6
46.6
60
N.A.
13.3
20
0
13.3
P-Site Similarity:
100
13.3
13.3
13.3
N.A.
100
93.3
N.A.
53.3
100
66.6
73.3
N.A.
33.3
60
26.6
26.6
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
7
7
7
7
0
0
20
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
34
0
27
0
20
0
7
67
0
7
34
0
27
% D
% Glu:
0
47
7
14
0
0
20
14
47
0
7
7
34
7
34
% E
% Phe:
0
0
0
0
0
0
0
20
7
7
0
0
7
0
7
% F
% Gly:
7
0
7
0
14
20
7
14
7
14
40
7
0
0
7
% G
% His:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
7
% H
% Ile:
0
7
0
0
20
0
0
7
0
0
0
0
0
7
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
14
14
7
7
0
7
0
0
0
0
0
7
0
7
0
% L
% Met:
0
0
0
0
7
7
14
0
0
0
0
54
0
0
0
% M
% Asn:
0
7
0
14
7
7
14
7
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
14
0
0
0
7
0
0
0
0
14
0
0
% P
% Gln:
0
0
7
7
0
7
7
0
0
7
0
0
0
7
0
% Q
% Arg:
14
0
0
0
0
40
7
0
7
7
7
7
0
7
0
% R
% Ser:
7
7
0
34
7
0
0
0
0
0
0
0
7
7
0
% S
% Thr:
54
0
7
0
0
7
7
0
0
0
20
14
0
20
0
% T
% Val:
0
0
7
0
14
0
0
0
27
0
0
0
0
40
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
7
0
0
0
20
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _